(R)-N-BOC-Propargylglycine(R)-N-tert-Butoxycarbonyl-2-amino-4-pentynoic acid - Names and Identifiers
(R)-N-BOC-Propargylglycine(R)-N-tert-Butoxycarbonyl-2-amino-4-pentynoic acid - Physico-chemical Properties
Molecular Formula | C10H15NO4
|
Molar Mass | 213.23 |
Density | 1.2177 (rough estimate) |
Boling Point | 353.22°C (rough estimate) |
Flash Point | 149.756°C |
Vapor Presure | 0mmHg at 25°C |
Appearance | Crystalline Powder |
Color | Off-white to light beige |
pKa | 3.53±0.10(Predicted) |
Storage Condition | 2-8°C |
Refractive Index | 1.4368 (estimate) |
(R)-N-BOC-Propargylglycine(R)-N-tert-Butoxycarbonyl-2-amino-4-pentynoic acid - Risk and Safety
Hazard Symbols | Xi - Irritant
|
Safety Description | 24/25 - Avoid contact with skin and eyes.
|
HS Code | 29224985 |
(R)-N-BOC-Propargylglycine(R)-N-tert-Butoxycarbonyl-2-amino-4-pentynoic acid - Introduction
(R)-N-BOC-Propargylglycine((R)-N-BOC-Propargylglycine) is an organic compound whose properties, uses, preparation and safety information are as follows:
Nature:
-Chemical formula: C12H17NO4
-Molecular weight: 239.27g/mol
-Appearance: Colorless solid
-Melting point: about 116-119°C
-Solubility: Soluble in organic solvents such as dimethyl sulfoxide (DMSO), methanol and ethanol
Use:
- (R)-N-BOC-Propargylglycine is an amino acid derivative widely used as a reagent in organic synthesis.
-It is often used in the synthesis of polypeptides, especially the construction of peptide sequences containing alkyne groups on amino acid side chains.
-It can also be used as a protecting group for amino acids, protecting the side chains of amino acids in organic synthesis to avoid accidental reactions.
Preparation Method:
The preparation of (R)-N-BOC-Propargylglycine is generally accomplished by chemical synthetic methods. One common synthetic route is by chemically reacting a propargyl haloalkyl compound with glycine to obtain the desired product.
Safety Information:
- (R)-The general safety of the N-BOC-Propargylglycine is relatively high, but attention should be paid to following the general laboratory safety operating procedures when handling.
-May be irritating to the eyes, skin and respiratory system, so avoid contact with it during operation.
-Avoid ignition and contact with oxidizing agents during handling and storage.
-Wear appropriate personal protective equipment such as gloves and safety glasses during use.
-In the event of inhalation, ingestion or skin contact, seek immediate medical assistance and provide the chemical name of the product and relevant information.
Last Update:2024-04-10 22:29:15